I bought my 05 Fz6 in October of '09, and a month later I hit a patch of sand in a hard left turn and didn't have the riding experience to deal with it. I paniced, the bike slid out and the rear wheel clipped the curb, hopping up and throwing me off of it. The bike did a complete flip, bounced a couple times, and landed upside-down with the engine running.
I completely snapped my leg in half, tib/fib both snapped and my leg was bent at a right angle. I couldn't walk for 4 months and I still have a hard time climbing up stairs now and then and my leg gives out on me. I have a titanium rod from my knee to my ankle with 6 pins.
The bike had frame sliders on it from the previous owner. The only damage to the bike was to a foot peg, my brake lever, and the right side of my headlight casing was cracked. I am absolutely convinced that without the sliders there would have been much more damage.
This really seems like a "grass is always greener" situation. Sometimes, the sliders will save your ass. Sometimes they'll increase potential damage. If I take mine off, I'll probably wish I had them on if I ever drop the bike again. If I leave then on, I'll probably wish I had taken them off. What's it called, Murphy's law? It boils down to personal preference - there will be times where it will save your bike and times where it does the exact opposite. I really don't think anybody can give a clear-cut response saying that for a fact they will save or damage your bike, it's completely situational.
Included bonus awesome xray pics of my leg! This is after they straightened it, I have other pics that are waaaaay worse.