I live accross the river in KY and work in Henderson. A guy I work with lives in E-ville and rides a R1. We've run up 66, 150, and I think 450. Not too bad, but just a few good sections on those roads. Plenty of scenery though.
62 to Leavenworth is a good ride, then you can take 66 down to the river or old 37 up to Paoli.